A US study of overweight dogs fed a reduced calorie, high-protein, high-fibre diet for 24 weeks found that the dogs’ body composition and inflammatory markers changed over time in ways that parallel the positive changes seen in humans on similar diets.
The dogs achieved a healthier weight without losing too much muscle mass, and their serum triglycerides, insulin and inflammatory markers all decreased with weight loss.
All such changes are beneficial, said University of Illinois Urbana-Champaign animal sciences professor Kelly Swanson, who led the new research.
Previous studies have shown that overweight and obesity lead to a shorter lifespan and a lower quality of life—in dogs and humans.
“Some of the problems we see in humans with obesity also occur in pet dogs,” Professor Swanson said.
Published in the Journal of Animal Science, the study is unusual in that it also measured changes in the dogs’ fecal microbiota over the course of losing weight.
Even though there are similarities in dog and human metabolism and digestive processes, dogs and humans differ in the species of microbes that inhabit the gut. These microbes perform similar functions, however. They metabolise proteins, carbohydrates and other molecules that are derived from food but escape digestion by the host; and they break down fibre to produce short-chain fatty acids that are important in regulating glucose and appetite, reducing inflammation, bolstering the immune system and providing energy to cells in the colon.
Some of the microbial changes observed in the dogs were difficult to interpret, but a reduction in fecal ammonia—probably the result of eating less protein on the calorie-restricted diet—was likely beneficial.
Dogs that lost weight also had increases in the proportion of bacteria of the genus Allobaculum. Higher Allobaculum populations correlated with an increase in fecal butyrate, a short-chain fatty acid that is a byproduct of the fermentation of dietary fibre. Previous studies have shown that butyrate has anti-inflammatory and anti-carcinogenic effects in the gut.
Most studies of gut microbiota focus on humans, so the new research offers insight into the similarities and differences between dogs and humans, and how they respond to dietary changes and weight loss.